Getting started

Talk to your doctor to choose the dosing regimen that works best for you

  • Stop (discontinue) prophylactic use of bypassing agents the day before starting HEMLIBRA prophylaxis.
  • You may continue prophylactic use of FVIII for the first week of HEMLIBRA prophylaxis.
  • For the first 4 weeks of treatment, you will take a loading dose once per week. This will increase the levels of HEMLIBRA in your blood. When the loading dose is complete, you will start taking a maintenance dose, which can be:

How should I take HEMLIBRA?

If your healthcare provider feels it's appropriate for you, HEMLIBRA may be self-injected after training. You should not inject HEMLIBRA without proper training by your healthcare provider.

Dosing information 

Your healthcare provider will determine your dose in milliliters (mL) that you will need to give based on your body weight. If your weight changes, do not change your dose or how often you take it without first talking to your healthcare provider.

As you prepare to start your treatment journey, carefully review the detailed Instructions for Use that comes with your HEMLIBRA for information on how to prepare and inject a dose of HEMLIBRA, and how to properly throw away used needles and syringes.

  • Use HEMLIBRA exactly as prescribed by your healthcare provider.
  • Stop (discontinue) prophylactic use of bypassing agents the day before starting HEMLIBRA prophylaxis.
  • You may continue prophylactic use of FVIII for the first week of HEMLIBRA prophylaxis.
  • HEMLIBRA is given as an injection under your skin (subcutaneous injection) by you or a caregiver.
  • Your healthcare provider should show you or your caregiver how to prepare, measure, and inject your dose of HEMLIBRA before you inject yourself for the first time.
  • Do not attempt to inject yourself or another person unless you have been taught how to do so by a healthcare provider.

What should I do if I miss a dose?

  • If you miss a dose of HEMLIBRA on your scheduled day, you should give the dose as soon as you remember. You must give the missed dose as soon as possible before the next scheduled dose, and then continue with your normal dosing schedule. Do not give two doses on the same day to make up for a missed dose.
  • HEMLIBRA may interfere with laboratory tests that measure how well your blood is clotting and may cause a false reading. Talk to your healthcare provider about how this may affect your care.

Always follow your healthcare provider’s instructions on when and how to treat a bleed when taking HEMLIBRA.

What are the HEMLIBRA vial strengths?

HEMLIBRA comes in four different vial strengths: 30 mg, 60 mg, 105 mg, and 150 mg. The strength and concentration are printed on the carton and vial label.

  • Always check the dosage strength printed on the label to ensure you are using the correct vials
  • Your healthcare provider will tell you which vials to use to prepare the dose that will work best for you
  • Depending on your dose, you may need to use more than one vial to give your total prescribed dose
  • Do not combine vials of different concentrations in one syringe
    • For example, as the 30 mg vial has a concentration of 30 mg/mL, it should not be mixed with the 60 mg, 105 mg, or 150 mg vials. Those three vials all have a concentration of 150 mg/mL

HEMLIBRA supplies

  • These are the primary supplies you will need to inject HEMLIBRA: a transfer needle, a syringe, and an injection needle
  • You can learn more about all the supplies you may need in the HEMLIBRA Instructions for Use that comes with your HEMLIBRA

Instructions for Use

Step-by-step instructions for administering HEMLIBRA

How to Inject HEMLIBRA

A video showing how to prepare and inject HEMLIBRA

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